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N. interosseus posterior syndrome, Anatomy

N. interosseus posterior is compressed in 60-70% of cases at Frohse’s arcade (upper edge of M. supinator). Less commonly in the radial tunnel, which extends from the upper edge of M. supinator and 5 cm distally

Frohse’s canal starts after the branch to the M. supinator

N. interosseus posterior syndrome, Clinic

N. interosseus posterior syndrome, Clinic
  • Caused by trauma, diabetic mononeuropathy, pressure from lipoma, ganglion, or hypertrophic synovitis in RA.
  • Pain in the lateral elbow region radiating distally; the nerve has no sensory function, so no sensory loss is detected in the skin. Pain can be provoked by compression 5 cm distal to the lateral humeral epicondyle.
  • Normal supination strength; innervation to M. supinator branches off before Frohse's arcade.
  • Normal strength in radial extension; innervation to M. extensor carpi radialis longus and M. extensor carpi radialis brevis branches off before Frohse's arcade.
  • No hand drop.
  • When attempting wrist extension, there is a radial deviation of the hand due to weak M. extensor carpi ulnaris, innervation to M. extensor carpi ulnaris arises in Frohse’s canal
  • Weakness in finger and thumb MCP extension, thumb IP extension, and thumb abduction

Posterior interosseous nerve syndrome, Supination test

Isometric supination increases the pain

Bäumer P, Kele H, Xia A, Weiler M, Schwarz D, Bendszus M, Pham M. Posterior interosseous neuropathy: Supinator syndrome vs fascicular radial neuropathy. Neurology. 2016 Nov 1;87(18):1884-1891.

Key diagnostics, N. radialis

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